STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2746Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (255 aa)    
Predicted Functional Partners:
pcaJ
Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit.
 
 0.918
pcaI
Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.
 
 
 0.915
mvaB
hydroxymethylglutaryl-CoA lyase; Isopropylmalate/homocitrate/citramalate synthases.
   
 
 0.900
ACPL_2745
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
   0.857
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.802
ACPL_4685
Purine catabolism regulatory protein; Regulator of polyketide synthase expression.
 
     0.787
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.708
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.708
ACPL_2747
Leu/Ile/Val-binding-like protein; ABC-type branched-chain amino acid transport systems, periplasmic component.
 
 
 
 0.661
ACPL_2748
Spermidine/putrescine import ATP-binding protein potA; ABC-type sugar transport systems, ATPase components.
 
     0.633
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.