STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_2804Putative amidohydrolase ytcJ; Predicted metal-dependent hydrolase with the TIM-barrel fold. (511 aa)    
Predicted Functional Partners:
ACPL_2805
L-erythro-3,5-diaminohexanoate dehydrogenase; NADPH:quinone reductase and related Zn-dependent oxidoreductases.
       0.797
mutL
Methylaspartate mutase.
       0.787
kamE
Beta-lysine 5,6-aminomutase; Predicted cobalamin binding protein.
       0.782
ACPL_2803
Beta-lysine 5,6-aminomutase.
       0.782
ACPL_2801
Acyl-CoA hydrolase.
       0.781
ACPL_2797
ytzA-like uncharacterized protein; Protein affecting phage T7 exclusion by the F plasmid.
  
  
 0.613
dpm-2
Dolichol-phosphate mannosyltransferase; Glycosyltransferases involved in cell wall biogenesis.
  
    0.570
ACPL_2806
Lysine 2,3-aminomutase.
       0.562
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
  0.552
gyrA-2
Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit.
     
  0.552
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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