Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2811Predicted esterase. (260 aa)    
Predicted Functional Partners:
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.944
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.944
ACPL_6195
Polyketide synthase modules and related proteins.
  
  
 0.895
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.791
ACPL_5453
Transcriptional regulator.
  
     0.652
tycC
Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.634
ppsC
Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.617
lgrB
Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.601
nrps2C
High-molecular-weight protein 2; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.580
ACPL_2564
Predicted flavoprotein involved in K+ transport.
  
     0.572
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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