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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phoDPhosphodiesterase/alkaline phosphatase D. (511 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase I.
    
 0.948
sulD
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.946
phoA-2
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
 
 0.940
phoD-2
Phosphodiesterase/alkaline phosphatase D.
  
  
 
0.915
ACPL_2831
Coagulation factor 5/8 type domain protein.
       0.797
glpQ
Glycerophosphoryl diester phosphodiesterase.
 
  
 0.522
ACPL_2615
Putative inorganic polyphosphate/ATP-NAD kinase; Predicted sugar kinase.
     
  0.499
ppnK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
  0.499
nadK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
  0.499
ACPL_2829
Abortive infection protein; Predicted metal-dependent membrane protease.
       0.490
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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