Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2857Anaerobic ribonucleoside-triphosphate reductase activating protein; Pyruvate-formate lyase-activating enzyme. (203 aa)    
Predicted Functional Partners:
ACPL_3065
6-pyruvoyl-tetrahydropterin synthase.
  
  
 0.918
ACPL_2856
Endonuclease/exonuclease/phosphatase family domain-containing protein 1; Transcriptional accessory protein.
 
     0.853
ACPL_2853
Putative AAA domain-containing protein; ATPases of the AAA+ class.
 
     0.832
ACPL_2854
Hypothetical protein.
       0.802
ACPL_2855
Hypothetical protein.
       0.802
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
     
 0.674
pdr1-2
Pleiotropic drug resistance protein 1; ABC-type multidrug transport system, permease component.
  
    0.659
ACPL_2858
Spermidine/putrescine import ATP-binding protein potA; ABC-type sugar transport systems, ATPase components.
       0.651
folE
GTP cyclohydrolase I.
  
  
 0.575
ACPL_7829
Uncharacterized protein; DNA repair photolyase.
     
 0.515
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.