STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgmAPhosphoglucomutase. (539 aa)    
Predicted Functional Partners:
malP
Starch phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.993
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.992
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
  
 0.953
tkt
Transketolase; Belongs to the transketolase family.
  
 
 0.944
ACPL_7488
Transketolase, N-terminal subunit.
  
 
 0.941
gtaB
UTP-glucose-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase.
    
 0.940
glgA
Glycogen synthase; Glycosyltransferase.
 
 0.936
acbQ
Acarbose 4-alpha-glucanotransferase.
 
 
 0.935
ppgK-2
Polyphosphate glucokinase; Transcriptional regulator/sugar kinase.
 
  
 0.932
rpiA
Ribose 5-phosphate isomerase.
  
 
 0.930
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.