Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2873Transcriptional regulator. (191 aa)    
Predicted Functional Partners:
ACPL_2872
tRNA (mo5U34)-methyltransferase; SAM-dependent methyltransferases.
 
 
   0.898
ACPL_6849
Clp domain protein.
  
     0.618
modR
Regulatory protein afsR.
  
     0.612
reg
55.5 kDa and 49.5 kDa sporulation protein.
  
     0.546
ACPL_2922
Hypothetical protein.
  
     0.538
ACPL_2309
Protein nirD; Transcriptional regulators.
  
     0.530
ACPL_1006
Asparagine synthase (glutamine-hydrolyzing).
  
     0.526
ACPL_639
Hypothetical protein.
  
     0.504
ACPL_7498
Lysozyme; Chitinase.
  
     0.468
ACPL_3696
Hypothetical protein.
  
     0.466
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (12%) [HD]