Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pknASerine/threonine protein kinase. (332 aa)    
Predicted Functional Partners:
prpH
Serine/threonine protein phosphatase.
 
 
 0.834
ACPL_5335
Serine/threonine protein phosphatase.
 
 
 0.828
ACPL_6617
Serine/threonine protein phosphatase.
 
 
 0.827
ACPL_162
Serine/threonine protein phosphatase.
 
 
 0.826
ACPL_5073
Oxoglutarate dehydrogenase inhibitor; FOG: FHA domain.
 
 
 
 0.669
amfT
Serine/threonine protein kinase.
  
     0.589
ACPL_160
Oxoglutarate dehydrogenase inhibitor; FOG: FHA domain.
 
 
 
 0.584
ACPL_2896
Hypothetical protein.
       0.581
ACPL_5209
Protein kinase and PP2C-like domain-containing protein; Serine/threonine protein phosphatase.
 
 
 0.557
ACPL_2897
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3; FOG: TPR repeat.
  
 
  0.489
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.