Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
paaIPhenylacetic acid degradation protein paaC. (293 aa)    
Predicted Functional Partners:
paaB
Phenylacetic acid degradation protein paaB; Uncharacterized enzyme of phenylacetate metabolism.
 
 0.999
paaK
Phenylacetic acid degradation NADH oxidoreductase; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
 
 0.998
paaA
phenylacetate-CoA oxygenase subunit PaaA.
  
  0.998
paaD
Phenylacetic acid degradation protein paaD; Predicted metal-sulfur cluster biosynthetic enzyme.
 
 
 0.994
chcB
Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.945
ACPL_5517
Enoyl-CoA hydratase/carnithine racemase.
  
 
 0.919
ACPL_2912
Retinal dehydrogenase 1; NAD-dependent aldehyde dehydrogenases.
 
  
 0.898
ACPL_5396
Oxidoreductase FAD-binding domain protein; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.
  
 0.849
ACPL_2913
Transcriptional regulator.
 
     0.811
paaX
Phenylacetic acid degradation operon negative regulatory protein paaX; Phenylacetic acid-responsive transcriptional repressor.
 
   
 0.584
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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