STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolD3D-(3,5/4)-trihydroxycyclohexane-1, 2-dione hydrolase; Acetolactate synthase; Belongs to the TPP enzyme family. (623 aa)    
Predicted Functional Partners:
iolB
5-deoxy-glucuronate isomerase; Uncharacterized enzyme involved in inositol metabolism.
 
 
 0.999
iolE
Inosose dehydratase; Sugar phosphate isomerases/epimerases.
 
 
 0.996
iolC
5-dehydro-2-deoxygluconokinase; Sugar kinases, ribokinase family.
 
  
 0.947
iolG
Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).
 
  
 0.935
ACPL_2917
ABC-type sugar transport system, periplasmic component.
 
  
 0.852
ACPL_2915
Simple sugar transport system ATP-binding protein; ABC-type spermidine/putrescine transport systems, ATPase components.
 
  
 0.840
ACPL_2916
Autoinducer 2 import system permease protein lsrC; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.
 
    0.804
ACPL_5407
PfkB domain protein; Sugar kinases, ribokinase family.
 
  
 0.741
ACPL_7750
Oxidoreductase domain-containing protein; Predicted dehydrogenases and related proteins.
 
  
 0.710
ACPL_5382
Oxidoreductase domain protein; Predicted dehydrogenases and related proteins.
 
  
 0.699
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.