close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manB-2Beta-mannosidase; Beta-galactosidase/beta-glucuronidase. (825 aa)    
Predicted Functional Partners:
manB-3
Beta-mannosidase; Beta-galactosidase/beta-glucuronidase.
  
  
 
0.906
ACPL_2944
Transcriptional regulators.
 
   
 0.830
bga-2
Beta-galactosidase.
 
 
 
 0.617
bga
Beta-galactosidase.
 
 
 
 0.604
axe1
Acetyl esterase (deacetylase).
 
     0.517
ACPL_4687
Uncharacterized protein conserved in bacteria.
  
     0.488
ACPL_5382
Oxidoreductase domain protein; Predicted dehydrogenases and related proteins.
  
   
 0.488
abfA
alpha-N-arabinofuranosidase; Alpha-L-arabinofuranosidase.
 
   
 0.486
ACPL_1513
PfkB domain protein; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).
   
    0.471
ACPL_6373
Phosphofructokinase; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.
   
    0.471
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (44%) [HD]