Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
manB-2Beta-mannosidase; Beta-galactosidase/beta-glucuronidase. (825 aa)    
Predicted Functional Partners:
manB-3
Beta-mannosidase; Beta-galactosidase/beta-glucuronidase.
  
  
 
0.906
ACPL_2944
Transcriptional regulators.
 
     0.825
bga-2
Beta-galactosidase.
 
 
 0.759
bga
Beta-galactosidase.
 
 
 0.751
ACPL_4099
Cellulase; Endoglucanase.
  
 
 0.578
celA
Endoglucanase.
  
 
 0.578
ACPL_5424
Beta-galactosidase; Belongs to the glycosyl hydrolase 35 family.
 
 
 0.551
abfA
alpha-N-arabinofuranosidase; Alpha-L-arabinofuranosidase.
 
   
 0.514
axe1
Acetyl esterase (deacetylase).
 
     0.512
ACPL_4687
Uncharacterized protein conserved in bacteria.
  
     0.488
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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