Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_2959Circadian clock protein KaiC; RecA-superfamily ATPases implicated in signal transduction. (485 aa)    
Predicted Functional Partners:
cyaC
Transcriptional regulatory protein resD; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   
 0.808
arcB-2
Multi-sensor signal transduction histidine kinase; Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
 
 0.574
ACPL_2272
Diguanylate cyclase; FOG: GAF domain.
 
 
 
 0.567
ACPL_3978
Putative integral membrane protein.
  
     0.555
ACPL_2016
Sensor histidine kinase and response regulator of a two component complex; FOG: PAS/PAC domain.
 
 
 
 0.547
ACPL_2273
Phytochrome A type 3; Signal transduction histidine kinase.
 
 
 
 0.527
ACPL_7621
Hypothetical protein.
 
     0.510
ACPL_5008
Histone acetyltransferase HPA2 and related acetyltransferases.
  
     0.505
ACPL_6332
Hypothetical protein; Zn-dependent proteases.
  
     0.499
ACPL_2223
Hypothetical protein.
  
     0.487
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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