STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2959Circadian clock protein KaiC; RecA-superfamily ATPases implicated in signal transduction. (485 aa)    
Predicted Functional Partners:
cyaC
Transcriptional regulatory protein resD; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   
 0.809
arcB-2
Multi-sensor signal transduction histidine kinase; Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
 
 0.592
ACPL_2272
Diguanylate cyclase; FOG: GAF domain.
 
 
 
 0.585
ACPL_2016
Sensor histidine kinase and response regulator of a two component complex; FOG: PAS/PAC domain.
 
 
 
 0.562
ACPL_3978
Putative integral membrane protein.
  
     0.555
ACPL_2273
Phytochrome A type 3; Signal transduction histidine kinase.
 
 
 
 0.546
ACPL_2260
Sensor histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 
 0.541
ACPL_4801
Signal transduction histidine kinase.
   
 
 0.521
ACPL_7621
Hypothetical protein.
 
     0.509
ACPL_5008
Histone acetyltransferase HPA2 and related acetyltransferases.
  
     0.505
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.