Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ACPL_298Transposase B; Integrase. (598 aa)    
Predicted Functional Partners:
ACPL_297
Hypothetical protein.
       0.825
ACPL_4015
Signal transduction protein; Predicted NTPase (NACHT family).
  
     0.712
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
    
 0.680
ACPL_5919
Transposase and inactivated derivatives.
 
   
 0.648
ACPL_5771
Hypothetical protein.
  
     0.596
fn1
Fibronectin; RTX toxins and related Ca2+-binding proteins.
  
     0.557
ACPL_299
Integrase family protein; Integrase.
       0.547
ACPL_5774
Hypothetical protein.
  
     0.543
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
 0.538
rpsI
Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
    
 0.538
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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