STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_2988Kynurenine formamidase; Predicted metal-dependent hydrolase. (231 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
  
 
 0.924
ACPL_7951
Hypothetical protein.
  
    0.801
ACPL_6187
Tryptophan 2,3-dioxygenase.
 
 
 0.787
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
  
 
 0.741
ACPL_2989
Putative transcriptional regulator, MerR family.
       0.566
ACPL_2990
Inter-alpha-trypsin inhibitor heavy chain H3; Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.
       0.558
ACPL_6188
Hypothetical protein.
  
  
 0.504
ACPL_5619
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 
     0.503
ACPL_5620
NADH-quinone oxidoreductase subunits H/I.
  
     0.497
ACPL_2628
Dyp-type peroxidase family protein; Predicted iron-dependent peroxidase.
  
     0.487
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.