STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lctPL-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (631 aa)    
Predicted Functional Partners:
ACPL_6088
L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.
 
  
 0.773
ACPL_2186
(S)-2-hydroxy-acid oxidase; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.
 
  
 0.772
ACPL_2316
Iron-sulfur cluster binding protein; Uncharacterized conserved protein containing a ferredoxin-like domain.
 
  
 0.757
ACPL_4163
Iron-sulfur cluster binding protein; Uncharacterized conserved protein containing a ferredoxin-like domain.
 
  
 0.757
ACPL_1974
L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.
  
  
 0.741
ACPL_3142
Lactic acid dehydrogenase; FAD/FMN-containing dehydrogenases.
  
  
 0.731
putA
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
  
 0.667
porA
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
  
  
 0.645
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
  
 0.587
ACPL_2317
Uncharacterized conserved protein containing a ferredoxin-like domain.
 
  
 0.567
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.