Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_302Protein icfG; Serine phosphatase RsbU, regulator of sigma subunit. (415 aa)    
Predicted Functional Partners:
ACPL_397
Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 0.805
rsbV-2
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
  
   0.771
rsbW
Serine-protein kinase rsbW; Anti-sigma regulatory factor (Ser/Thr protein kinase).
  
   0.771
prpF-2
Phosphoserine phosphatase rsbP; Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.760
ACPL_3894
Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.755
prpF
Phosphoserine phosphatase rsbP; Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.754
ACPL_1370
Multi-sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.745
rsbV
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
  
   0.742
rsbU-3
Uncharacterized protein; Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.741
ACPL_5313
Serine phosphatase RsbU, regulator of sigma subunit.
  
     0.736
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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