STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yvoAMannosyl-D-glycerate transport/metabolism system repressor mngR; Transcriptional regulators. (241 aa)    
Predicted Functional Partners:
trpB-2
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.853
nadR
Transcriptional regulator nadR; FAD synthase.
   
    0.792
trpA-2
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
       0.782
ACPL_4171
Fatty acid metabolism regulator protein; Transcriptional regulators.
  
    0.635
ACPL_4174
Transcriptional regulators.
  
    0.605
ACPL_7189
Hypothetical protein; Predicted transcriptional regulator.
  
  
 0.601
dgoR
Fatty acid metabolism regulator protein; Transcriptional regulators.
  
    0.580
ACPL_3701
HTH-type transcriptional activator rhaS; AraC-type DNA-binding domain-containing proteins.
  
  
 0.579
ACPL_4189
Fatty acid metabolism regulator protein; Transcriptional regulators.
  
    0.575
ACPL_3020
Outer membrane lipoprotein-sorting protein.
       0.550
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.