Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3030Hypothetical protein; Zn-dependent protease with chaperone function. (305 aa)    
Predicted Functional Partners:
copY
Predicted transcriptional regulator.
 
 
  0.996
ACPL_3279
Hypothetical protein; Predicted transcriptional regulator.
 
    0.734
ACPL_4433
Hypothetical protein; Predicted transcriptional regulator.
 
    0.665
cydCD
Multidrug resistance protein 2; ABC-type multidrug transport system, ATPase and permease components.
       0.606
cydA
Cytochrome bd-type quinol oxidase, subunit 1.
       0.592
cydB
Cytochrome bd-type quinol oxidase, subunit 2.
       0.584
ACPL_3385
Hypothetical protein; Predicted transcriptional regulator.
 
    0.573
cydR
Transcriptional regulator.
       0.545
ACPL_2109
AAA ATPase central domain protein; ATP-dependent Zn proteases; Belongs to the AAA ATPase family.
   
 0.538
ftsH
Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.538
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.