STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cydCDMultidrug resistance protein 2; ABC-type multidrug transport system, ATPase and permease components. (1360 aa)    
Predicted Functional Partners:
cydA
Cytochrome bd-type quinol oxidase, subunit 1.
 
  
 0.998
cydB
Cytochrome bd-type quinol oxidase, subunit 2.
 
  
 0.998
cydR
Transcriptional regulator.
       0.773
copY
Predicted transcriptional regulator.
       0.632
ACPL_3030
Hypothetical protein; Zn-dependent protease with chaperone function.
       0.601
coaE
dephospho-CoA kinase/unknown domain fusion protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.597
manR
Mandelate racemase; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
      
 0.424
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
      
 0.424
ACPL_6509
Hypothetical protein.
      
 0.424
ctaE
Heme/copper-type cytochrome/quinol oxidase, subunit 3.
      
 0.422
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.