Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_3045yojA-like uncharacterized permease; H+/gluconate symporter and related permeases. (459 aa)    
Predicted Functional Partners:
ACPL_1948
Gluconokinase; Gluconate kinase.
 
  
 0.774
gnd2
6-phosphogluconate dehydrogenase.
 
  
 0.716
glxK
Glycerate kinase; Belongs to the glycerate kinase type-1 family.
 
  
 0.713
ACPL_3046
Transcriptional regulators.
       0.682
xylB
Xylulokinase; Glycerol kinase.
  
  
 0.628
aqp4
Aquaporin-4; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
   
 0.526
ACPL_4770
Glycerol kinase; Sugar (pentulose and hexulose) kinases.
 
  
 0.494
acpD
FMN-dependent NADH-azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.
     
 0.493
ACPL_2738
Transcriptional regulators.
  
  
 0.436
kdgA
2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase.
 
   
 0.424
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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