Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_305Midasin; AAA ATPase containing von Willebrand factor type A (vWA) domain. (352 aa)    
Predicted Functional Partners:
aprA-2
Peptidase S8/S53 subtilisin kexin sedolisin; Subtilisin-like serine proteases; Belongs to the peptidase S8 family.
 
 0.550
ACPL_304
Hypothetical protein.
       0.541
ACPL_303
Hypothetical protein.
       0.530
ACPL_6911
Collagen alpha-4(VI) chain; Secreted and surface protein containing fasciclin-like repeats.
  
 0.517
rpgR
X-linked retinitis pigmentosa GTPase regulator; Alpha-tubulin suppressor and related RCC1 domain-containing proteins.
  
  
  0.449
ACPL_6719
Proprotein convertase subtilisin/kexin type 6; Subtilisin-like serine proteases; Belongs to the peptidase S8 family.
  
 
  0.431
ACPL_3137
Hypothetical protein.
   
 0.424
ACPL_6704
Protease; Subtilisin-like serine proteases; Belongs to the peptidase S8 family.
  
 
  0.401
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.