ACPL_308 protein (Actinoplanes sp. SE50110) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ACPL_308

Hypothetical protein; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor). (107 aa)

Predicted Functional Partners:

prsR-2

0.860

ACPL_4649

0.770

ACPL_397

0.721

ACPL_3780

0.716

ACPL_381

0.701

ACPL_306

0.642

ACPL_2318

0.573

ACPL_7226

0.551

ACPL_2274

0.542

ACPL_379

0.541

Your Current Organism:

Actinoplanes sp. SE50110

NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACPL_2274	ACPL_2318	ACPL_2274	ACPL_2318	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Signal transduction histidine kinase.	0.995
ACPL_2274	ACPL_306	ACPL_2274	ACPL_306	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Signal transduction histidine kinase.	0.968
ACPL_2274	ACPL_308	ACPL_2274	ACPL_308	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Hypothetical protein; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	0.542
ACPL_2274	ACPL_3780	ACPL_2274	ACPL_3780	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Magnesium or manganese-dependent protein phosphatase; FOG: PAS/PAC domain.	0.979
ACPL_2274	ACPL_379	ACPL_2274	ACPL_379	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Acetoacetate metabolism regulatory protein atoC; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.	0.960
ACPL_2274	ACPL_381	ACPL_2274	ACPL_381	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Phosphoserine phosphatase rsbX; Anti-sigma regulatory factor (Ser/Thr protein kinase).	0.949
ACPL_2274	ACPL_397	ACPL_2274	ACPL_397	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Serine phosphatase RsbU, regulator of sigma subunit.	0.966
ACPL_2274	ACPL_4649	ACPL_2274	ACPL_4649	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	0.998
ACPL_2274	ACPL_7226	ACPL_2274	ACPL_7226	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Multi-sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	0.993
ACPL_2274	prsR-2	ACPL_2274	ACPL_307	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	Putative anti-sigma regulatory factor, serine/threonine protein kinase; Signal transduction histidine kinase.	0.596
ACPL_2318	ACPL_2274	ACPL_2318	ACPL_2274	Signal transduction histidine kinase.	Two-component system, cell cycle sensor kinase and response regulator; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.	0.995
ACPL_2318	ACPL_306	ACPL_2318	ACPL_306	Signal transduction histidine kinase.	Signal transduction histidine kinase.	0.943
ACPL_2318	ACPL_308	ACPL_2318	ACPL_308	Signal transduction histidine kinase.	Hypothetical protein; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).	0.573
ACPL_2318	ACPL_3780	ACPL_2318	ACPL_3780	Signal transduction histidine kinase.	Magnesium or manganese-dependent protein phosphatase; FOG: PAS/PAC domain.	0.981
ACPL_2318	ACPL_379	ACPL_2318	ACPL_379	Signal transduction histidine kinase.	Acetoacetate metabolism regulatory protein atoC; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.	0.974
ACPL_2318	ACPL_381	ACPL_2318	ACPL_381	Signal transduction histidine kinase.	Phosphoserine phosphatase rsbX; Anti-sigma regulatory factor (Ser/Thr protein kinase).	0.958
ACPL_2318	ACPL_397	ACPL_2318	ACPL_397	Signal transduction histidine kinase.	Serine phosphatase RsbU, regulator of sigma subunit.	0.972
ACPL_2318	ACPL_4649	ACPL_2318	ACPL_4649	Signal transduction histidine kinase.	Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	0.999
ACPL_2318	ACPL_7226	ACPL_2318	ACPL_7226	Signal transduction histidine kinase.	Multi-sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.	0.996
ACPL_2318	prsR-2	ACPL_2318	ACPL_307	Signal transduction histidine kinase.	Putative anti-sigma regulatory factor, serine/threonine protein kinase; Signal transduction histidine kinase.	0.625