Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_313Uncharacterized protein conserved in bacteria. (97 aa)    
Predicted Functional Partners:
ACPL_311
yxaF-like uncharacterized HTH-type transcriptional regulator; Transcriptional regulator.
 
     0.836
ACPL_5909
yxaF-like uncharacterized HTH-type transcriptional regulator; Transcriptional regulator.
 
     0.775
gltB
Glutamate synthase domain 2.
       0.576
pclO-2
Protein piccolo; Type V secretory pathway, adhesin AidA.
  
     0.543
zan-2
Zonadhesin; RTX toxins and related Ca2+-binding proteins.
  
    0.536
ACPL_6212
Hypothetical protein; Predicted transcriptional regulators.
  
     0.522
ACPL_4253
Hypothetical protein.
 
     0.510
bhp
Serine-rich adhesin for platelets; RTX toxins and related Ca2+-binding proteins.
  
     0.496
nemA
NADH:flavin oxidoreductases, Old Yellow Enzyme family.
       0.433
ACPL_1654
Phosphoenolpyruvate carboxylase; Hydrolases of the alpha/beta superfamily.
 
     0.419
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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