STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3149WD-40 repeat-containing serine/threonine protein kinase; NAD(+) hydrolase (NADase) that catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide. (720 aa)    
Predicted Functional Partners:
ACPL_3150
WD-40 repeat-containing serine/threonine protein kinase; FOG: WD40 repeat.
 
    
0.778
ACPL_3980
Putative WD repeat-containing protein; FOG: WD40 repeat.
 
     0.756
ACPL_6128
Putative WD repeat-containing protein; FOG: WD40 repeat.
  
     0.737
ACPL_3321
Tetratricopeptide repeat protein 28; FOG: TPR repeat.
 
 
  0.688
ACPL_5840
Nephrocystin-3; FOG: TPR repeat.
  
 
  0.671
ACPL_3728
Nephrocystin-3; FOG: TPR repeat.
  
 
  0.649
ACPL_438
Non-specific serine/threonine protein kinase; Superfamily II DNA/RNA helicases, SNF2 family.
 
 
 0.556
ACPL_5267
Hypothetical protein.
    
 0.555
helZ
Helicase HelZ; Superfamily II DNA/RNA helicases, SNF2 family.
 
 
 0.545
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.540
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.