Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
ACPL_3209Thrombin-like enzyme gussurobin; Secreted trypsin-like serine protease. (291 aa)    
Predicted Functional Partners:
pks2A
Polyketide synthase modules and related proteins.
    
 0.674
pks1B
Polyketide synthase modules and related proteins.
    
 0.672
pks3B
Polyketide synthase modules and related proteins.
    
 0.672
ACPL_3980
Putative WD repeat-containing protein; FOG: WD40 repeat.
  
 
 0.668
sprU
Anionic trypsin-2; Secreted trypsin-like serine protease.
  
     0.659
acuC
Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
  
 
  0.649
ACPL_1580
Hypothetical protein; ATPases involved in chromosome partitioning.
  
 
   0.607
dnaK-3
Molecular chaperone.
    
 0.602
ank2
Ankyrin-2; FOG: Ankyrin repeat.
  
 
 0.586
gadB
Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family.
  
 0.585
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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