Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
puoMonoamine oxidase. (453 aa)    
Predicted Functional Partners:
ACPL_6380
Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.
    
 0.916
ACPL_7671
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
   
 0.910
ACPL_7755
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
   
 0.910
acuC
Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
   
 0.858
helZ
Helicase HelZ; Superfamily II DNA/RNA helicases, SNF2 family.
    
 0.716
ACPL_438
Non-specific serine/threonine protein kinase; Superfamily II DNA/RNA helicases, SNF2 family.
    
 0.716
ACPL_3218
Vacuolar cation/proton exchanger 2; Ca2+/Na+ antiporter.
       0.686
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
   
 0.575
ACPL_1778
Hypothetical protein; ATP-dependent Lon protease, bacterial type.
    
  0.555
ACPL_2464
NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
   
 0.550
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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