Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3276Hypothetical protein. (184 aa)    
Predicted Functional Partners:
ACPL_3277
Hypothetical protein.
 
  
 0.920
ACPL_3275
Hypothetical protein.
 
     0.881
ACPL_5793
Hypothetical protein.
    
  0.703
ruvA
Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
     
  0.687
ACPL_7625
Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily.
 
  
  0.578
ACPL_6058
HTH-type transcriptional regulator malT; DNA-binding HTH domain-containing proteins.
  
     0.575
ACPL_7626
Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily.
 
  
  0.569
aveR
HTH-type transcriptional regulator malT; Predicted ATPase.
  
     0.566
cs1
L-asparagine oxygenase.
  
     0.544
pcrA
Superfamily I DNA and RNA helicases.
 
  
  0.528
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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