STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ykoHATPase domain-containing protein; Signal transduction histidine kinase. (471 aa)    
Predicted Functional Partners:
tcrA
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.959
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
 
 
0.900
ACPL_4801
Signal transduction histidine kinase.
 
 
 0.899
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
 
 
 0.886
rcaC
Protein rcaC; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.845
tcrA-2
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.826
mprA
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.821
ACPL_2932
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.814
phoB-2
Phosphate regulon transcriptional regulatory protein phoB; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.812
ACPL_2205
Two component transcriptional regulator, winged helix family; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
   0.806
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.