STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_332ydhO-like uncharacterized protein; Cell wall-associated hydrolases (invasion-associated proteins). (330 aa)    
Predicted Functional Partners:
ACPL_6351
Putative channel-forming protein.
   
 
 0.862
ftsE
Methionine import ATP-binding protein metN; Part of the ABC transporter FtsEX involved in cellular division.
 
 
 0.715
ACPL_2060
Calcineurin-binding protein cabin-1; Serine/threonine protein kinase.
  
  
 0.623
cwlM
N-acetylmuramoyl-L-alanine amidase.
 
  
 0.613
ACPL_1080
Macrolide export ATP-binding/permease protein macB; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 
 0.601
ACPL_1269
D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase cwlS; Cell wall-associated hydrolases (invasion-associated proteins).
 
  
0.521
sepF
Cell division protein sepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
   
 0.498
acm2
Lysozyme; Muramidase (flagellum-specific).
  
 
 
 0.488
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
  
 0.479
rodA
Bacterial cell division membrane protein; Belongs to the SEDS family.
  
  
 0.466
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.