Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACPL_3357Hydrolase; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). (253 aa)    
Predicted Functional Partners:
ACPL_3358
Hypothetical protein.
       0.773
ACPL_3359
Hypothetical protein.
       0.689
ACPL_3360
Hypothetical protein.
       0.689
ACPL_3361
Putative S-adenosyl-L-methionine-dependent methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
       0.689
sucA
2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.
   
 0.686
ACPL_3356
Putative hydrolase; Ketosteroid isomerase homolog.
       0.603
stuC
Osmosensitive K+ channel histidine kinase.
   
  0.566
ACPL_1533
2-oxoisovalerate dehydrogenase E1 component; Transketolase.
   
 0.545
ACPL_3124
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
   
 0.545
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.532
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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