STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbs-2Cysteine synthase. (371 aa)    
Predicted Functional Partners:
ACPL_335
Multidrug resistance protein mdtH; Permeases of the major facilitator superfamily.
 
  
 0.983
ACPL_548
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 
 0.913
cysA
Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.748
metB
Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.745
megL
Methionine-gamma-lyase; Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.733
ACPL_7742
Hypothetical protein; Acetyltransferase (isoleucine patch superfamily).
  
 
 0.727
ACPL_6716
Laccase-12; Putative multicopper oxidases.
  
  
 0.689
gltB
Glutamate synthase domain 2.
     
 0.682
sat1
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.674
cobG
precorrin-3B synthase; Sulfite reductase, beta subunit (hemoprotein).
 
  
 0.494
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.