STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3379Putative transcriptional regulator ycf27; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (126 aa)    
Predicted Functional Partners:
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
 
 
 0.968
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
 
 
 0.965
ACPL_398
GAF sensor hybrid histidine kinase; FOG: HAMP domain.
  
 
 0.953
ACPL_2318
Signal transduction histidine kinase.
 
 
 0.949
ACPL_7207
Integral membrane sensor hybrid histidine kinase; Signal transduction histidine kinase.
 
 
 0.944
ACPL_4649
Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
  
 
0.936
ACPL_3427
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase.
 
 
 0.933
ACPL_4800
Two-component system, cell cycle sensor kinase and response regulator; Signal transduction histidine kinase.
 
 
 0.932
ACPL_2260
Sensor histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.930
etr2-2
Ethylene receptor 2; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 0.928
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.