STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3390Hypothetical protein. (415 aa)    
Predicted Functional Partners:
ACPL_3389
GMP synthase; Glutamine-hydrolyzing; ATP-utilizing enzymes of the PP-loop superfamily.
 
  
 0.986
ACPL_4834
NCAIR mutase (PurE)-related proteins.
 
  
 0.941
ACPL_1974
L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.
    
 0.903
ACPL_6088
L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.
    
 0.903
ACPL_6525
Zn-dependent hydrolases, including glyoxylases.
     
  0.900
larC
Hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.882
ACPL_3391
Prestalk A differentiation protein A; Predicted nucleoside-diphosphate-sugar epimerases.
       0.645
ACPL_3388
Hypothetical protein.
       0.586
uxaC
Glucuronate isomerase.
 
     0.496
ACPL_3392
Microtubule-associated protein 1A; Uncharacterized protein conserved in bacteria with the myosin-like domain.
       0.479
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.