STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3392Microtubule-associated protein 1A; Uncharacterized protein conserved in bacteria with the myosin-like domain. (106 aa)    
Predicted Functional Partners:
chiA-3
Chitinase; Belongs to the glycosyl hydrolase 18 family.
    
 
 0.597
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.585
ACPL_3391
Prestalk A differentiation protein A; Predicted nucleoside-diphosphate-sugar epimerases.
   
   0.577
ACPL_3389
GMP synthase; Glutamine-hydrolyzing; ATP-utilizing enzymes of the PP-loop superfamily.
       0.479
ACPL_3390
Hypothetical protein.
       0.479
bar
Phosphinothricin acetyltransferase; Sortase and related acyltransferases.
       0.477
ACPL_7611
Superfamily I DNA and RNA helicases.
  
 
 0.476
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.412
gyrB-2
Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.
   
 
 0.412
acuC
Deacetylases, including yeast histone deacetylase and acetoin utilization protein.
   
 0.403
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.