Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
ACPL_3425Phosphate regulon transcriptional regulatory protein phoB; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (155 aa)    
Predicted Functional Partners:
mtrB
Two-component system, OmpR family, sensor histidine kinase MtrB; Signal transduction histidine kinase.
  
  0.939
ACPL_6800
yclJ-like uncharacterized transcriptional regulatory protein; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  
  0.923
ACPL_1066
Transcriptional regulatory protein yycF; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  
 
0.922
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
 
 
 0.887
ACPL_3427
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Osmosensitive K+ channel histidine kinase.
 
 
 0.885
ACPL_2318
Signal transduction histidine kinase.
  
 
 0.833
phoR-3
Sensory box histidine kinase PhoR; Signal transduction histidine kinase.
 
 
 0.832
phoR-5
Sensory box histidine kinase PhoR; Signal transduction histidine kinase.
 
 
 0.831
ACPL_4809
Two-component system sensor protein; Signal transduction histidine kinase.
 
 
 0.815
ACPL_4800
Two-component system, cell cycle sensor kinase and response regulator; Signal transduction histidine kinase.
 
 
 0.813
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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