STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3451Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family. (109 aa)    
Predicted Functional Partners:
ACPL_4649
Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
  
 
 0.799
ACPL_397
Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 0.782
ACPL_3780
Magnesium or manganese-dependent protein phosphatase; FOG: PAS/PAC domain.
 
 
 0.760
ACPL_381
Phosphoserine phosphatase rsbX; Anti-sigma regulatory factor (Ser/Thr protein kinase).
 
 
 0.738
ACPL_379
Acetoacetate metabolism regulatory protein atoC; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
   0.676
ACPL_486
Putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.617
ACPL_2318
Signal transduction histidine kinase.
  
  
 0.579
barA
Sensory box histidine kinase/response regulator; Signal transduction histidine kinase.
  
  
 0.562
ACPL_7226
Multi-sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
  
 
 0.561
ACPL_2108
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
  
     0.557
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.