Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3488Hypothetical protein. (447 aa)    
Predicted Functional Partners:
ACPL_6249
Glucose kinase; Transcriptional regulator/sugar kinase.
  
     0.721
ACPL_6251
L-threonine 3-dehydrogenase; Zn-dependent alcohol dehydrogenases.
  
     0.681
ACPL_5031
Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
     0.599
ACPL_3489
Hypothetical protein.
 
     0.539
ACPL_3490
Helix-turn-helix domain-containing protein.
 
     0.529
acbM
2-epi-5-epi-valiolone 7-kinase; Catalyzes the conversion of 2-epi-5-epi-valiolone to 2-epi-5- epi-valiolone 7-phosphate. Involved in the biosynthesis of the acarviose moiety of the alpha-glucosidase inhibitor acarbose. Belongs to the ROK (NagC/XylR) family.
  
     0.493
ACPL_4880
Hypothetical protein.
  
     0.488
ACPL_2840
Hypothetical protein.
  
     0.475
ACPL_4881
DNA-binding protein.
  
     0.472
ACPL_1065
Hypothetical protein.
  
     0.461
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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