STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3498Uncharacterized protein; Type IV secretory pathway, VirB4 components. (578 aa)    
Predicted Functional Partners:
ACPL_3497
Hypothetical protein.
 
  
 0.966
ACPL_3499
Hypothetical protein; Predicted ATPase.
 
  
 0.965
ACPL_3496
Hypothetical protein.
 
   
 0.958
ACPL_3495
Hypothetical protein.
 
   
 0.957
ACPL_3494
Hypothetical protein.
 
   
 0.900
ACPL_3500
3-oxoacyl-[acyl-carrier-protein] synthase 3.
 
     0.861
ACPL_3510
Hypothetical protein; Response regulator containing CheY-like receiver and SARP domains.
  
     0.629
ACPL_3508
Otogelin; Uncharacterized protein containing LysM domain.
  
     0.549
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.466
ACPL_3501
Transposase, IS4 family protein; Transposase and inactivated derivatives.
       0.439
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.