STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dprAProtein smf; Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake. (286 aa)    
Predicted Functional Partners:
ACPL_1391
ComE operon protein 3; Predicted membrane metal-binding protein.
 
  
 0.835
ACPL_7263
Uncharacterized protein; Predicted ATPase with chaperone activity.
 
 
 0.802
ACPL_3514
Hypothetical protein.
       0.718
ACPL_4649
Response regulator receiver sensor signal transduction histidine kinase; Serine phosphatase RsbU, regulator of sigma subunit.
  
  
 0.620
ACPL_6938
Hypothetical protein; Orotate phosphoribosyltransferase.
  
 
 0.606
phoA-2
Alkaline phosphatase; Belongs to the alkaline phosphatase family.
  
    0.602
parA
Formate-tetrahydrofolate ligase; ATPases involved in chromosome partitioning.
  
  
 0.595
ACPL_7262
Uncharacterized protein; Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.
 
    0.574
ACPL_1069
Hypothetical protein; Predicted amidophosphoribosyltransferases.
  
 
 0.573
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.570
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.