Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
muc4Mucin-4; PPE-repeat proteins. (2809 aa)    
Predicted Functional Partners:
ACPL_2896
Hypothetical protein.
  
 
   0.537
dprA
Protein smf; Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
       0.519
ACPL_6911
Collagen alpha-4(VI) chain; Secreted and surface protein containing fasciclin-like repeats.
  
 0.517
ACPL_3137
Hypothetical protein.
 
 
 0.491
ACPL_3514
Hypothetical protein.
       0.480
ACPL_5001
Endoglucanase; Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.450
ACPL_6866
G-protein coupled receptor 98; RTX toxins and related Ca2+-binding proteins.
  
     0.446
ACPL_7314
Histone-lysine N-methyltransferase MLL3.
 
     0.433
aprA-2
Peptidase S8/S53 subtilisin kexin sedolisin; Subtilisin-like serine proteases; Belongs to the peptidase S8 family.
  
 0.427
ACPL_5237
Signal peptidase I.
  
     0.424
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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