Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_353NAD-dependent epimerase/dehydratase; dTDP-D-glucose 4,6-dehydratase. (330 aa)    
Predicted Functional Partners:
mpg2
Nucleotidyl transferase; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).
 
 
 0.994
ACPL_355
ADP-L-glycero-D-manno-heptose-6-epimerase; Nucleoside-diphosphate-sugar epimerases.
 
 
0.904
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes.
  
  
 0.878
ACPL_357
Uncharacterized protein.
 
     0.794
ACPL_356
Spherulin-4.
 
     0.793
icsA
Glycogen synthase; Glycosyltransferase.
 
  
 0.791
ACPL_3097
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
  
 0.744
acbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis; Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
  
 0.739
galT-2
Galactose-1-phosphate uridylyltransferase.
   
 
 0.735
ACPL_350
Hypothetical protein.
 
    0.692
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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