Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACPL_3576ADP-ribosylglycohydrolase. (429 aa)    
Predicted Functional Partners:
ACPL_3575
Hypothetical protein; Pyrimidine reductase, riboflavin biosynthesis.
       0.648
ACPL_3577
Macrolide export ATP-binding/permease protein macB; ABC-type antimicrobial peptide transport system, permease component.
       0.634
ACPL_3578
Spermidine/putrescine import ATP-binding protein potA; ABC-type sugar transport systems, ATPase components.
       0.634
ACPL_5412
Uncharacterized protein conserved in bacteria.
 
   
 0.486
ACPL_3579
Oxygen sensor histidine kinase nreB; Signal transduction histidine kinase, glucose-6-phosphate specific.
       0.459
ACPL_3580
Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
       0.459
kptA
Putative RNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
 
   
 0.446
ACPL_5567
ADP-ribose 1''-phosphate phosphatase; Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.
 
   
 0.423
ACPL_6494
Collagen alpha-2(I) chain; Superfamily II DNA and RNA helicases.
  
     0.412
ACPL_6944
Hypothetical protein.
  
     0.406
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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