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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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afsRRegulatory protein afsR; DNA-binding transcriptional activator of the SARP family. (963 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.928
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.925
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 0.899
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.871
nadR
Transcriptional regulator nadR; FAD synthase.
   
    0.822
hrdB
RNA polymerase principal sigma factor hrdB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.773
ACPL_3597
Radical SAM domain-containing protein; Fe-S oxidoreductase.
       0.773
ACPL_3598
Hypothetical protein.
       0.773
rpoT
RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.773
sigB
RNA polymerase principal sigma factor hrdB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.773
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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