STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
afsR-2Regulatory protein afsR; Predicted ATPase. (1003 aa)    
Predicted Functional Partners:
nadR
Transcriptional regulator nadR; FAD synthase.
   
    0.773
ACPL_7865
Hypothetical protein; Predicted phosphatases.
   
    0.773
ACPL_7632
Chromosome initiation inhibitor; Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
   
    0.769
ACPL_3915
Carbohydrate diacid regulator; Regulator of polyketide synthase expression.
   
    0.768
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
  
 0.684
ACPL_5319
Membrane-bound protein lytR; Transcriptional regulator.
   
    0.649
ACPL_8294
Membrane-bound protein lytR; Transcriptional regulator.
   
    0.649
ACPL_2813
Transcriptional regulators.
   
    0.634
ACPL_2966
HTH-type transcriptional regulator betI; Uncharacterized protein conserved in bacteria.
   
    0.631
ACPL_1870
Predicted transcriptional regulator.
   
    0.629
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.