STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppiBPutative peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (230 aa)    
Predicted Functional Partners:
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
  
 
 0.886
nrps1A
Amino acid adenylation domain-containing protein; Non-ribosomal peptide synthetase modules and related proteins.
   
 
 0.882
nrps1B
Non-ribosomal peptide synthetase modules and related proteins.
   
 
 0.882
nrps1D
Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.882
ACPL_6193
Non-ribosomal peptide synthetase modules and related proteins.
   
 
 0.882
pks2A
Polyketide synthase modules and related proteins.
  
 
 0.880
pks1B
Polyketide synthase modules and related proteins.
   
 
 0.872
pks3B
Polyketide synthase modules and related proteins.
   
 
 0.872
htpG-2
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
 
 0.699
ACPL_6666
Pre-mRNA-processing ATP-dependent RNA helicase PRP5; Superfamily II DNA and RNA helicases.
 
 0.674
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.