Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3635Protein essC; DNA segregation ATPase FtsK/SpoIIIE and related proteins. (1445 aa)    
Predicted Functional Partners:
ACPL_3634
Hypothetical protein.
 
     0.817
ACPL_3636
Protein of unknown function DUF909; Belongs to the WXG100 family.
 
 
 
 0.615
ACPL_465
Uncharacterized protein conserved in bacteria; Belongs to the WXG100 family.
   
 
 0.607
ftsQ
FtsQ-like cell division protein; Essential cell division protein.
   
 0.546
ACPL_224
Hypothetical protein.
   
 0.546
ACPL_4425
Hypothetical protein.
   
 0.546
ACPL_6923
Hypothetical protein.
   
 0.546
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 0.525
ftsE
Methionine import ATP-binding protein metN; Part of the ABC transporter FtsEX involved in cellular division.
   
 
 0.446
ACPL_4396
Hypothetical protein; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.
 
     0.446
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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