STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acbDAcarviose transferase (ATase); Belongs to the glycosyl hydrolase 13 family. (724 aa)    
Predicted Functional Partners:
acbE
Acarbose resistent alpha-amylase; Belongs to the glycosyl hydrolase 13 family.
 
  
0.740
malE
Maltose-binding periplasmic proteins/domains.
 
  
 0.715
acbZ
Alpha-amylase; Glycosidases; Belongs to the glycosyl hydrolase 13 family.
 
  
0.594
acbB
dTDP-glucose 4,6-dehydratase; Probably involved in the biosynthesis of the acarviose moiety of the alpha-glucosidase inhibitor acarbose. Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D- xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction (By similarity). Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
      
 0.580
malF
ABC-type sugar transport systems, permease components.
 
  
 0.521
malR
Transcriptional regulator, LacI family; Transcriptional regulators.
  
  
 0.506
acbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis; Belongs to the glucose-1-phosphate thymidylyltransferase family.
   
  
 0.503
cgt
Cyclomaltodextrin glucanotransferase; Glycosidases.
 
   
 0.502
acbR
1-epi-valienol-1, 7-bisphosphate-1-adenylyltransferase.
  
  
 0.493
acbQ
Acarbose 4-alpha-glucanotransferase.
  
  
 0.486
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.