Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3728Nephrocystin-3; FOG: TPR repeat. (790 aa)    
Predicted Functional Partners:
ACPL_2334
Putative WD repeat-containing protein; FOG: WD40 repeat.
  
 
  0.742
ACPL_6129
Putative WD repeat-containing protein; FOG: WD40 repeat.
  
 0.734
ACPL_3980
Putative WD repeat-containing protein; FOG: WD40 repeat.
 
 0.713
ACPL_6128
Putative WD repeat-containing protein; FOG: WD40 repeat.
  
 
  0.703
ACPL_3617
Putative WD repeat-containing protein; FOG: WD40 repeat.
  
 
  0.667
ACPL_3149
WD-40 repeat-containing serine/threonine protein kinase; NAD(+) hydrolase (NADase) that catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide.
  
 
  0.654
ACPL_3150
WD-40 repeat-containing serine/threonine protein kinase; FOG: WD40 repeat.
  
 
  0.637
dnaK-3
Molecular chaperone.
  
 0.618
ogt-2
UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase 110 kDa subunit; FOG: TPR repeat.
 
 
 0.615
ACPL_6916
Putative WD repeat-containing protein; FOG: WD40 repeat.
  
 0.600
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (12%) [HD]