Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACPL_3739Beta-lactamase class C and other penicillin binding proteins. (380 aa)    
Predicted Functional Partners:
baeN
Thiotemplate mechanism natural product synthetase; Non-ribosomal peptide synthetase modules and related proteins.
 
  
 0.712
ACPL_578
Uncharacterized proteins, homologs of microcin C7 resistance protein MccF.
 
  
  0.576
ACPL_3737
DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
       0.535
ACPL_3738
Hypothetical protein.
       0.535
ACPL_1303
Glycosyl transferase family protein; Membrane carboxypeptidase (penicillin-binding protein).
   
 
 0.520
ACPL_4159
Glycosyl transferase family protein; Membrane carboxypeptidase (penicillin-binding protein).
   
 
 0.520
ponA
Glycosyl transferase family protein; Membrane carboxypeptidase (penicillin-binding protein).
   
 
 0.520
ACPL_8116
Glycosyl transferase family protein; Membrane carboxypeptidase (penicillin-binding protein).
   
 
 0.520
ACPL_8350
Membrane carboxypeptidase (penicillin-binding protein).
   
 
 0.520
pbpA
Peptidoglycan glycosyltransferase; Cell division protein FtsI/penicillin-binding protein 2.
     
 0.518
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (26%) [HD]