STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhaANa(+)/H(+) antiporter nhaA 1; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (437 aa)    
Predicted Functional Partners:
mscL
Large-conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.578
ACPL_5514
ydcN-like uncharacterized HTH-type transcriptional regulator; Predicted transcriptional regulators.
  
    0.499
ACPL_3771
Protein of unknown function DUF1469.
       0.496
ACPL_3772
Laminin subunit beta-2.
       0.496
ACPL_1774
Hypothetical protein.
   
    0.457
ACPL_2029
Uncharacterized protein conserved in bacteria.
   
    0.457
ACPL_2094
Transcription-repair coupling factor (superfamily II helicase).
   
    0.457
ACPL_2097
Hypothetical protein.
   
    0.457
ACPL_2508
Tetratricopeptide repeat protein 28; Uncharacterized protein conserved in bacteria.
   
    0.457
ACPL_3235
Hypothetical protein.
   
    0.457
Your Current Organism:
Actinoplanes sp. SE50110
NCBI taxonomy Id: 134676
Other names: A. sp. SE50/110, Actinoplanes sp. (strain 50/110), Actinoplanes sp. 50/110, Actinoplanes sp. SE50/110
Server load: low (38%) [HD]